Analyst report
Acridine Derivatives as Inhibitors of the IRE1a-XBP1 Pathway Cytotoxic to Human Multiple Myeloma
Using a luciferase reporter–based high-throughput chemical library screen and topological data analysis, we identified Nacridine-9-yl-N',N' dimethylpropane-1,3-diamine (DAPA) as an inhibitor of the inositol...
Using a luciferase reporter–based high-throughput chemical library screen and topological data analysis, we identified Nacridine-9-yl-N',N' dimethylpropane-1,3-diamine (DAPA) as an inhibitor of the inositol...Read more